The production of the John Deere 5R series was moved to the USA, and shortly thereafter the model range disappeared from the European markets for a few years. It returned renewed at the end of 2016. The new model range still featured 4.5-liter engines without urea injection. Power ranged from 90 to 125 hp, and with the additional power feature, an extra 10 hp was available at road speeds. The transmission was 16+16, now equipped with an electro-hydraulic range shift. Automatic shifting was available at an additional cost. In the Command8 version, the four-speed quick shift was replaced by an 8-speed. In this version, 40 km/h speed was reached at 1760 rpm. All models featured as standard an automatic clutch introduced by a few other manufacturers, allowing the tractor to be stopped and crawled simply by pressing the brake pedal. The maximum speed was always 40 km/h. The basic version had an open hydraulic system, but output was 96 l/min. An optional load-sensing hydraulic system with 117 l/min was available.

In terms of structure, the 5R differed from most other Deere models: it did not have a separate frame; instead, the engine was part of the load-bearing structure. The weight was 4300 kg, clearly more than the previous model. The cab was new, and the instrument panel was placed on the front pillar. The windshield was a single piece. Optional extras included, among others, electrically operated hydraulic valves, suspension on the Carraro front axle, cab suspension, and from 2018 onwards, an armrest with control devices familiar from larger models. In addition to the standard model, a narrow 1.7-meter-wide version was also available.

For 2019, automatic steering and variable steering ratio were introduced.

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