In the autumn of 2001, the last English Massey Ferguson was renewed. Model numbers rose by 100 points from 4200 to 4300. The most visible new feature was the pillar exhaust pipe on the 4-cylinder models. The controls in the cab were largely renewed, the most notable being the levers of the mechanical lift and the short gear lever, which operated stiffly. At the front, the front weight bracket was 10 cm further forward than before. The noise level had decreased to 78 decibels. The tractor was still available with a low cab and a slanted hood. The front axle of the 4345 was now the same as in the larger models.

The four-cylinder engines were also equipped with Fastram combustion chambers. Performance figures remained unchanged except for the 4345, which was fitted with a wastegate turbo, but the power was now rated according to ISO TR14396. Shutdown was now via the ignition key also on the 4-cylinder models. As before, the standard transmission was 8+8 in the 3-cylinder models and 12+12 in the 4-cylinder models, equipped with a mechanical reverser. For an additional cost, a creeper gear and a hydraulic reverser were available, the latter implemented with one clutch pack for forward and one for reverse. Equipment was now offered in packages similar to the 6200 series, but the hydraulic reverser, creeper gear, and electric lift raised the price to a non-competitive level.

MF production in England ended at the end of 2002. The Peri was never manufactured in France; instead, stocks made in England were used up during 2003, and thereafter the 4300 series was replaced by the 5400 series.

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