From the MF 6400 series, the six-cylinder models were introduced in the summer of 2003, and by the end of that year the lineup was rounded out with four four-cylinder tractors. On the models below 150 HP the engines were supplied by Perkins. Except for the two smallest four-cylinder units, they all featured electronic engine management and an intercooler. The transmission was the Dynashift with a four-speed powershift, already used in earlier series, but now the 40 km/h top speed was reached at just 1,880 rpm (unlike the earlier 6445/6455). The quick-shift function for range-gear changes was standard.

The basic hydraulic system remained an open-center design with a 58 l/min pump. Optional equipment included a 100 l/min pump or, more commonly, a closed-center system with a 110 l/min pump. The cab was modernized and declared noise level was 71 dB, although that figure applied only to certain models. Standard equipment was fairly modest. Optional extras, available individually or in packages, included automatic gear shifting, a suspended front axle, cab suspension, and electro-hydraulic valves. A power-boost feature (power figures shown in parentheses) was also available as an option. The boost became active in the 3rd and 4th gears of the range gearbox—i.e., from just under 10 km/h upward. The oil-change interval was extended to 400 hours.

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